一、基本信息
姓 名:王利文
性 别:女
学历/学位:研究生/工学博士
职务职称:副教授、硕士生导师
所在部门:河北农业大学jxf吉祥官网总站食品质量与安全系(D座1408室)
通讯地址:河北省保定市河北农业大学jxf吉祥官网总站食品质量与安全系
邮政编码:071001
联系电话:18522918696
电子邮箱:liwenwang@hebau.edu.cn
二、主要学术及社会兼职(注明兼职起止时间)
河北省现代农业产业体系淡水养殖创新团队加工岗位成员
兼任国际食物营养与安全协会秘书
《Food Science and Human Wellness》青年编委
《International Journal of Food Science and Technology》荣誉副编辑
《LWT》、《Food Chemistry》《Journal of Agricultural and Food Chemistry》等国内外学术期刊审稿人
“科创中国”保定青年智库专家
三、学习工作经历
2017.09 - 2020.12:新西兰林肯大学,食品科学与分子营养,博士;
2013.09 - 2017.06:天津商业大学,发酵工程,硕士;
2009.09 - 2013.07:内蒙古农业大学,食品科学与工程,学士
四、主讲课程及研究方向
1、主讲课程:《食品质量与安全专业导论(双语)》、《人体生理学概论》、《食品质量管理学》、《科技论文写作》、《食品营养与健康》。
2、研究方向:淀粉类主食产品加工研究、果蔬加工副产物中天然功能因子功效评价及保健功能食品的开发,以及水产资源及副产物高值化利用与新产品创制。
五、主要研究成果、近年承担的科研项目及获奖情况
1.主持国家自然科学基金青年项目“基于AhR配体解析香菇柄不溶性膳食纤维-多酚结合物调控肠黏膜屏障的分子机制”
2.主持河北省自然科学基金春晖人才项目“基于胆汁酸稳态探究香菇柄不溶性膳食纤维对肝脏脂代谢的调控机制”
3.主持河北省省属高等学校基本科研业务费研究项目“食用菌膳食纤维差异性结合胆汁酸的动力学规律及构效关系研究”
4.主持河北农业大学引进人才科研专项“以肠肝轴为靶点的食用菌中天然产物的肠粘膜屏障保护作用”
5.主持并完成新西兰林肯大学博士科研基金“The molecular and physicochemical mechanism by which mushroom functional food products affect obesity, diabetes and neurodegeneration”
6.参研国家区域创新发展联合基金“板栗营养组分及其在食品加工过程中的变化规律研究”
7.参研国家重点研发计划“板栗产业关键技术研发与新产品创制”
8.参研国家自然科学基金“陈皮黄酮抑制肠道菌群TMAO生成及预防动脉粥样硬化机理研究”
9.参研河北省重点研发计划“河鲀加工副产物的综合利用关键技术研究”
六、代表性论文
以第一作者或通讯作者在国内外学术期刊发表多篇科研论文,其中SCI收录20余篇,代表性论文如下:
1.Liwen Wang, Margaret Brennan, Shiming Li, Hui Zhao, Klaus W. Lange, Charles Brennan, (2022) How does the Tea L-Theanine Buffer Stress and Anxiety. Food Science and Human Wellness. 11(3), 467–475. https://doi.org/10.1016/j.fshw.2021.12.004 (中科院一区,TOP)
2.Liwen Wang,Wenqiang Guan, Jianfu Liu, Hui Zhao, Charles Brennan. (2021). Edible mushrooms dietary fibre and antioxidants: Effects on glycaemic load manipulation and their correlations pre-and post-simulated in vitro digestion. 351, 129320 (2021). Food Chemistry. doi: 10.1016/j.foodchem.2021.129320 (中科院一区,TOP)
3.Liwen Wang,Hui Zhao, Margaret Brennen, Xiang Wen, Jingwen He, Meiyan Wang, Wenqiang Guan, Jianfu Liu, Charles Brennan. (2020).In vitrogastric digestion antioxidant and cellular radical scavenging activities of wheat-shiitake noodles. Food Chemistry. 2020 330, 127214. doi: 10.1016/j.foodchem.2020.127214. (中科院一区,TOP)
4.Liwen Wang, Guliang Yang, Li Yuan, Yiwen Yang, Hui Zhao, Chi-Tang Ho, and Shiming Li. (2019) Green Tea Catechins Effectively Altered Hepatic Fibrogenesis in Rats by Inhibiting ERK and Smad1/2 Phosphorylation. Journal of Agricultural and Food Chemistry. 2019 67(19), 5437-5445. doi: 10.1021/acs.jafc.8b05179 (中科院一区,TOP)
5.Tao Long*,Liwen Wang*, Yiwen Yang, Li Yuan, Hui Zhao, Guliang Yang, Chi-Tang Ho, Shiming Li. (2019). Protective Effect of Trans-2,3,5,4'-tetrahydroxystilbene 2-O-β-D-glucopyranoside on Liver Fibrosis and Renal Injury Induced by CCl4via Activating p-ERK1/2 and p-Smad1/2. Food & Function. 2019 10(8), 5115–5123. (* authors contributed equally to the papers) doi: 10.1039/C9FO01010F (中科院一区,TOP,共一)
6.Liwen Wang, Minxiong Pan, Chih-Yu Lo, Hui Zhao, Shiming Li, Chi-Tang Ho, Guliang Yang. (2018). Anti-fibrotic activity of polyphenol-enriched sugarcane extract in rats via inhibition of p38 and JNK phosphorylation. Food & Function. 2018 9(2), 951-958. doi: 10.1039/C7FO01617D (中科院一区,TOP)
7.Liwen Wang,Zhiwei Yue, Mengzheng Guo, Lianying Fang, Liang Bai, Xinyu Li, Yongqing Tao, Suying Wang, Qiang Liu, Dexian Zhi, Hui Zhao. (2016). Dietary Flavonoid Hyperoside Induces Apoptosis of Activated Human LX-2 Hepatic Stellate Cell by Suppressing Canonical NF-kappaB Signaling. BioMed Research International. 2016, 1068528. doi: 10.1155/2016/1068528 (中科院三区)
8.Liwen Wang, Jinhan Wang, Lianying Fang, Zuliang Zheng, Dexian Zhi, Suying Wang, Shiming Li, Chi-Tang Ho, and Hui Zhao. (2014). Anticancer activities of citrus peel polymethoxyflavones related to angiogenesis and others. BioMed Research International. 2014, 453972. doi: 10.1155/2014/453972 (中科院三区)
七、编写教材、著作
参编《Pathology: Oxidative Stress and Dietary Antioxidants》. 2020, 289-296. ISBN 978-0-12-815972-9. Academic Press. doi: 10.1016/B978-0-12- 815972-9.00028-7